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Particles Engineered for Drug Delivery

Industry-Leading CDMO Advancing Next-Horizon LNPs, PNPs, and Polymeric Microspheres

Phosphorex empowers innovators to advance complex therapeutics through innovative drug delivery platforms, including LNPs, PNPs, and polymeric microspheres. With scientific creativity, deep technical expertise, and a highly collaborative scientific team, we help innovators overcome therapeutic drug-targeting and patient-safety challenges and accelerate programs from feasibility through preclinical development.

Advancing Innovative Drug Delivery

Phosphorex drives innovation in lipid nanoparticle, polymeric nanoparticle, and sustained-release microsphere drug delivery through integrated formulation optimization, scalable process development, and CMC strategy, ensuring consistent performance from the lab to the clinic.

Lipid Nanoparticles

Phosphorex is delivering the next generation of LNPs, unlocking even greater possibilities for delivering nucleic acids to extra-hepatic tissues and achieving cell-specific targeting.

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Polymeric Nanoparticles

We achieve precise targeting using biodegradable polymers and their copolymers with polyethylene glycol (PEG), ensuring the payload reaches its destination while protecting it from degradation.

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Polymeric Microspheres

Sustained-release microsphere formulations encapsulate small molecules, peptides, and proteins using biodegradable polymers, thereby prolonging drug exposure and reducing dosing frequency.

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The Phosphorex Drug Delivery Engine

The Phosphorex Drug Delivery Engine assembles the core capabilities required to propel advanced delivery systems from concept to clinic. By integrating formulation optimization, process design and CMC, analytical expertise, and tech transfer with process optimization and troubleshooting, we advance consistent, scalable, and clinically relevant drug delivery development.

Formulation Optimization

Driving the design of precise, scalable formulations, Phosphorex leverages advanced particle engineering and instrumentation. Our expert optimization aligns next-horizon delivery performance with manufacturability and clinical intent.

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Process Design & CMC

Phosphorex powers process design and CMC with expertise that defines critical quality attributes, implements robust control strategies, and enables reproducible, scalable manufacturing of complex delivery systems to advance clinical outcomes.

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Analytical Expertise

Propel product understanding, leveraging complex analytical methods that address the challenges of encapsulating payloads in particulate-based drug delivery systems. Our analytical approach is built for clarity, product understanding, and efficient decision-making.

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Tech Transfer, Process Optimization & Troubleshooting

Accelerate transfer of preclinical processes utilizing our well-crafted tech transfer playbook, work with our GMP partners to optimize processes, and troubleshoot as needed to de-risk your journey to the clinic and market.

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Diverse Modality & Payload Experience

Phosphorex delivers solutions across modalities and payloads, supporting cell therapies, gene and RNA medicines, vaccines, oncology, and long-acting injectables through targeted carriers optimized for diverse payloads, highly effective clinical translation, and scalable manufacturing.

Diverse Modality & Payload Experience

Updates & Expertise

Leveraging Advanced Drug Delivery Systems to Improve Clinical Viability
Articles

Leveraging Advanced Drug Delivery Systems to Improve Clinical Viability

Development of Long-Acting Injectable Microspheres
Case Studies

Development of Long-Acting Injectable Microspheres

Post-Assembly Functionalization of Maleimide-Derivatized Lipid Nanoparticles with Peptide and Antibody Ligands via Thiol-Maleimide Conjugation Chemistry
Technical Bulletins

Post-Assembly Functionalization of Maleimide-Derivatized Lipid Nanoparticles with Peptide and Antibody Ligands via Thiol-Maleimide Conjugation Chemistry

Subject Matter Expert Video Series | Iro Vinales, Ph.D.
Videos

Subject Matter Expert Video Series | Iro Vinales, Ph.D.

Webinar on Demand | From Bench to Scale: Scaling Biodegradable mRNA Lipid Nanoparticle for Clinical Success
Webinars

Webinar on Demand | From Bench to Scale: Scaling Biodegradable mRNA Lipid Nanoparticle for Clinical Success

The LNP Alliance Is Dedicated to Accelerating Lipid Nanoparticle Drug Development

LNP Alliance

The LNP Alliance brings together Phosphorex, NOF CORPORATION, NeoSome Life Sciences, NanoImaging Services, and Envol Biomedical to provide an integrated, end-to-end platform for lipid nanoparticle development, combining proprietary lipids, formulation and process expertise, advanced analytics, imaging, and preclinical evaluation to accelerate delivery of next-generation therapeutics to the clinic efficiently.

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We Deliver

No matter the complexity or scientific creativity required, we'll partner to bring your therapeutic concept to life.

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