Material Safety Data Sheet- Plain PLGA
Section 1: Chemical Product and Company Identification
Part Name: Plain Degradex® PLGA Dry Polymer Microspheres and Nanospheres
Supplier: Phosphorex, LLC, 35 Parkwood Dr. Suite 150, Hopkinton, MA 01748
Section 2: Composition / Information on Ingredients
Plain Poly (D,L-Lactic Acid-co-Glycolic Acid) (50:50) dry microspheres and nanospheres
Section 3: Hazards Identification
Eyes: No guide established. May cause reversible irritation.
Skin Contact: No guide established. May cause reversible irritation.
Inhalation: May cause lung irritation.
Systemic: Acute: If inhaled in large quantities, may cause reversible lung irritation.
Chronic: If inhaled in large quantities, may cause reversible lung irritation.
Reproductive and developmental toxicity: Ingredients are not considered reproductive or developmental toxicants.
Carcinogenicity: Ingredients are not listed by NTP, IARC or OSHA as carcinogens.
Medical conditions aggravated by exposure: None known.
Section 4: First Aid Measures
Eyes: Flushing the eye immediately with water for 15 minutes is a good safety practice. If irritation develops, seek medical advice.
Skin: Contact may cause slight irritation. Wash off in flowing water or shower. Wash clothing before reuse. Treat as any contact dermatitis. If burn is present, treat as any thermal burn.
Ingestion: Drink one to two glasses of water and seek medical advice. Induce vomiting if large amounts are ingested.
Inhalation: Remove to fresh air if effects occur. Consult medical personnel.
Systemic & Other Effects: Human effects not established. No specific antidote. Treatment based on sound judgment of physician and the individual reactions of the patient.
Section 5: Fire Fighting Measures
Flammable/explosiveness: Not flammable. As with all finely divided organic powders, should be considered combustible.
Fire Fighting Instruction: Use extinguishing media appropriate for surrounding fire (water, foam, vaporizing liquid or multipurpose dry chemical).
Section 6: Accidental Release Measures
Any information listed below is to be considered in addition to internal guidelines for isolation of spill, containment of spill, removal of ignition sources from immediate area, and collection for disposal of spill by trained, properly protected clean up personnel.
Avoid unnecessary exposure and contact.
Section 7: Handling and Storage
Ventilation: Good room ventilation usually adequate for most operations.
Respiratory Protection: None normally needed. In cases where there is a likelihood of inhalation exposure to dried particles, wear NIOSH approved dust respirator.
Storage: Keep tightly sealed to prevent contamination. Store in a -20ºC dry environment. Avoid damaging or puncturing containers.
Section 8: Exposure Controls / Personal Protection
Respiratory Protection: None normally needed. In cases where there is a likelihood of inhalation exposure to dried particles, wear a NIOSH approved dust respirator.
Wash / Hygienic Practices: Wash with soap and water when leaving work area and before eating, smoking, and using restroom facilities.
Section 9: Physical and Chemical Properties
Melting Point: 250ºC / 482ºF
Density: 1.25-1.35 g/cc
Solubility: Insoluble
Appearance: white fluffy powder
Section 10: Stability and Reactivity
Stability: Stable under normal conditions. See Section 7.
Hazardous Decomposition Products: Not known.
Hazardous Polymerization: Will not occur.
Section 11: Toxicological Information
no data
Section 12: Ecological Information
no data
Section 13: Disposal Considerations
All waste containing the product should be specially contained, properly labeled, and stored separately from other facility waste discharges. Dispose of any waste residues according to prescribed federal, state, and local guidelines (e.g., to an appropriately permitted chemical waste incinerator). Rinse waters resulting from spill cleanups should be discharged in an environmentally safe manner.
Section 14: Transportation Data
no data
Section 15: Regulatory Information
no data
Section 16: Other Information
PHOSPHOREX, LLC provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. Individuals receiving this information must exercise their independent judgment in determining its appropriateness for a particular purpose.
PHOSPHOREX, LLC makes no representations or warranties, either expressed or implied, of merchantability, fitness for particular purposes with respect to the information set forth herein or to which the information refers. Accordingly, PHOSPHOREX, LLC will not be responsible for damages resulting from the use of or reliance upon this information.